How Colossal Bioscience is bringing back extinct animals

How Colossal Bioscience is bringing back extinct animals - Science Feed

Colossal Biosciences is a biotechnology and genetic engineering company that works on de-extinction of animals lost long ago. This company has got success at revival of Dire Wolf and Woolly Mouse.

The company seeks to revive the important species like Mammoth, Dodo, Tasmanian Tiger and many more. The company was founded on September 13, 2021.

The one of the most successful project has been of Dire Wolf. For the first time in entire human history, they created three dire wolf pups named as Khaleesi, Romulus and Remus. The growth timeline is as follows: Neonatal, Transitional, Socialization, Ranking, Adolescence and Adult. Currently, age of Romulus and Remus is of 6 months and Khaleesi is of 3 months.

Colossal used the advanced multiplex gene editing technology for this. Their team successfully introduced gene edits at 20 loci and 14 genes. This was done for gene restoration. The team found LCORL (Ligand Dependent Nuclear Receptor Corepressor Like) in canids which was dire wolf variant of a well-known gene.

Colossal is also trying to find vaccine for deadly EEHV (Elephant Endotheliotropic Herpes Virus) found in elephants. There are many more projects they are working on.

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